CJC-1295 (sin DAC)CJC-1295 (sin DAC), también conocido como GRF modificado (1-29), es un péptido que comprende 29 aminoácidos y es un análogo sintetizado químicamente de la hormona liberadora de la hormona del crecimiento (GHRH). Este péptido es químicamente similar a la GHRH (tiene sustituciones de aminoácidos en solo 4 posiciones), pero se diferencia en el sentido de que permanece activo en el torrente sanguíneo durante más tiempo. Se ha demostrado que CJC-1295 aumenta la hormona del crecimiento (GH) y factor de crecimiento similar a la insulina (lGF-1) en humanos sin reacciones adversas graves. Un estudio realizado en 2001 demostró que CJC-1295 era seguro y, en general, bien tolerado en pacientes que recibieron un régimen de 14 días administrado por vía subcutánea.Ipamorelínlpamorelin is a selective GH-Secretagogue and ghrelin receptor agonist. The potency ofghrelin stimulation can be compared to GHRP6 with less appetite stimulation propertiesHowever, unlike other GH-Secretagogues this pentapeptide doesn't release the samevolumes of cortisol, acetylcholine, prolactin and aldosterone. lt is for this reasonlpamorelin has been considered the first selective GH-Secretagogue.TesamorelinaTesamorelin is growth-hormone-releasing analog that can increase lGF-1 levels in bothmen and women by an average of 181 micrograms/liter. This growth hormone can bindand stimulate the GHRH receptors that have a similar potency with GHRH. lt binds andstimulates human GHRH receptors with similar potency as endogenous GHRH. it has ahost of other benefits including nootropic effects and reducing triglycerides. Tesamorelinhas subsequently been shown to decrease carotid intima media thickness (clMT).visceral adipose tissue (VAT), and C-reactive proteins (CRP) in a recent study. it has notbeen shown to significantly affect other pituitary hormones and their respectivemechanisms in the body. Additionally, it has been shown to improve cognitive function forhealthy older adults and also for people with mild cognitive impairment who are at anincreased risk of progressing to Alzheimer's disease.ResumenCJC-1295, lpamorelin, and Tesamorelin are typically compounded together due to theirability to stimulate GHRH for enhanced results. Research reports accelerated fat loss,improved sleep, mood, increased energy, as well as long term growth hormone production with lpamorelin. That is especially evident when programmatically combinedwith CJC 1295. After a cycle, the body sees a prolonged boost in hGH production farbeyond their initial dose, thus allowing longer-term maintenance of benefits.
Tesamorelin also improves the overall framework of the body. This peptide works well forindividuals 30+ since the production of GH naturally begins to lower as we age and ithelps improve it. Physical activity supports the release of GH as well. This peptide is themildest growth hormone-releasing peptide and also the most versatile one. it is said to bethe most suitable peptide as it doesn't induce these side effects like desensitization,hunger stimulation, or unnecessary plasma growth, like other peptides.
Research has shown that the net effect of combining the three peptides results inincreased GH secretion and IGF-1 levels, increased muscle growth, increased bonedensity, improved cognitive function and memory, increased cellular repair andregeneration, increased fat loss, and more.
CJC-1295, lpamorelin, and Tesamorelin exhibits minimal side effects, low oral andexcellent subcutaneous bioavailability in mice. Per kg dosage in mice does not scale tohumans. CJC-1295, lpamorelin, and Tesamorelin for sale at PEPTIDE GURUS is limited toeducational and scientific research only, not for human consumption. Only buy CJC-1295lpamorelin, and Tesamorelin if you are a licensed researcher.Citas referenciadas:1.Teichman,S.L., Neale,A.,Lawrence, B., Gagnon, C., Castaigne, J.P. andFrohman, L.A.(2006)'Prolonged stimulation of growth hormone (GH) and insulin.like growth factor l secretion by CJC-1295, a long-acting analog of GH-releasinghormone, in healthy adults',J Clin Endocrinol Metab,91(3), pp.799-805.
2.Sackmann-Sala, L., Ding, J., Frohman, L.A. and Kopchick, J.J.(2009)'Activationof the GH/GF-1 axis by CJC-1295, a long-acting GHRH analog, results in serumprotein profile changes in normal adult subjects', Growth Horm /GF Res,19(6), pp471-7.
3.Onescu, M. and Frohman, L.A. (2006) 'Pulsatile secretion of growth hormone (GH)persists during continuous stimulation by CJC-1295, a long-acting GH-releasinghormone analog', J Clin Endocrinol Metab,91(12),pp.4792-7.
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The products offered on this website are furnished for in-vitro studies only. in-vitro studies(Latin: in alass) are performed outside of the body, These products are not medicines ordrugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals isstrictly forbidden by law.
