CJC-1295 (без ЦАП)CJC-1295 (без DAC), также известный как ModifiedGRF (1-29), представляет собой пептид, который содержит 29 аминокислот и представляет собой химически синтезированный аналог гормона, высвобождающего гормон роста (GHRH). Этот пептид химически подобен GHRH (он имеет аминокислотные замены всего в 4 положениях), но отличается тем, что остается активным в кровотоке в течение более длительного времени. Было показано, что CJC-1295 увеличивает выработку гормона роста (GH) и инсулиноподобный фактор роста (lGF-1) у людей без каких-либо серьезных побочных реакций. Исследование, проведенное в 2001 году, показало, что CJC-1295 безопасен и в целом хорошо переносится пациентами, получавшими 14-дневный курс лечения подкожно.Ипаморелинlpamorelin is a selective GH-Secretagogue and ghrelin receptor agonist. The potency ofghrelin stimulation can be compared to GHRP6 with less appetite stimulation propertiesHowever, unlike other GH-Secretagogues this pentapeptide doesn't release the samevolumes of cortisol, acetylcholine, prolactin and aldosterone. lt is for this reasonlpamorelin has been considered the first selective GH-Secretagogue.ТесаморелинTesamorelin is growth-hormone-releasing analog that can increase lGF-1 levels in bothmen and women by an average of 181 micrograms/liter. This growth hormone can bindand stimulate the GHRH receptors that have a similar potency with GHRH. lt binds andstimulates human GHRH receptors with similar potency as endogenous GHRH. it has ahost of other benefits including nootropic effects and reducing triglycerides. Tesamorelinhas subsequently been shown to decrease carotid intima media thickness (clMT).visceral adipose tissue (VAT), and C-reactive proteins (CRP) in a recent study. it has notbeen shown to significantly affect other pituitary hormones and their respectivemechanisms in the body. Additionally, it has been shown to improve cognitive function forhealthy older adults and also for people with mild cognitive impairment who are at anincreased risk of progressing to Alzheimer's disease.Краткое содержаниеCJC-1295, lpamorelin, and Tesamorelin are typically compounded together due to theirability to stimulate GHRH for enhanced results. Research reports accelerated fat loss,improved sleep, mood, increased energy, as well as long term growth hormone production with lpamorelin. That is especially evident when programmatically combinedwith CJC 1295. After a cycle, the body sees a prolonged boost in hGH production farbeyond their initial dose, thus allowing longer-term maintenance of benefits.
Tesamorelin also improves the overall framework of the body. This peptide works well forindividuals 30+ since the production of GH naturally begins to lower as we age and ithelps improve it. Physical activity supports the release of GH as well. This peptide is themildest growth hormone-releasing peptide and also the most versatile one. it is said to bethe most suitable peptide as it doesn't induce these side effects like desensitization,hunger stimulation, or unnecessary plasma growth, like other peptides.
Research has shown that the net effect of combining the three peptides results inincreased GH secretion and IGF-1 levels, increased muscle growth, increased bonedensity, improved cognitive function and memory, increased cellular repair andregeneration, increased fat loss, and more.
CJC-1295, lpamorelin, and Tesamorelin exhibits minimal side effects, low oral andexcellent subcutaneous bioavailability in mice. Per kg dosage in mice does not scale tohumans. CJC-1295, lpamorelin, and Tesamorelin for sale at PEPTIDE GURUS is limited toeducational and scientific research only, not for human consumption. Only buy CJC-1295lpamorelin, and Tesamorelin if you are a licensed researcher.Ссылки на цитаты:1.Teichman,S.L., Neale,A.,Lawrence, B., Gagnon, C., Castaigne, J.P. andFrohman, L.A.(2006)'Prolonged stimulation of growth hormone (GH) and insulin.like growth factor l secretion by CJC-1295, a long-acting analog of GH-releasinghormone, in healthy adults',J Clin Endocrinol Metab,91(3), pp.799-805.
2.Sackmann-Sala, L., Ding, J., Frohman, L.A. and Kopchick, J.J.(2009)'Activationof the GH/GF-1 axis by CJC-1295, a long-acting GHRH analog, results in serumprotein profile changes in normal adult subjects', Growth Horm /GF Res,19(6), pp471-7.
3.Onescu, M. and Frohman, L.A. (2006) 'Pulsatile secretion of growth hormone (GH)persists during continuous stimulation by CJC-1295, a long-acting GH-releasinghormone analog', J Clin Endocrinol Metab,91(12),pp.4792-7.
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