Successful wound healing depends on fibroblasts, which regulate extracellular matrixproduction, as well as cells of the immune system. For these cells to do their jobs, theyneed to move to the location of injury. This movement, called migration, is heavilydependent the protein actin. Both BPC-157 and TB-500 are important in actin regulation.BPC-157 works at the level of the gene to increase actin production. TB-500, an actinbinding protein, helps to sequester actin in areas where it is most useful for buildingfilaments from actin to allow for cell movement2. Together, BPC-157 and TB-500 worksynergistically to increase the quantity and function of actin and thus increase the rate atwhich fibroblasts and cells of the immune system migrate to areas of injury.