PotensiBPC-157 dan TB-500Synergy di WoundRepairPenelitian mengungkapkan bahwa BPC-157 dan TB-500, yang keduanya membantu merangsang jalur penyembuhan luka yang berbeda, mungkin memiliki efek sinergis ketika digabungkan bersama-sama.Migrasi selPenyembuhan luka yang berhasil tergantung pada fibroblas, yang mengatur produksi matriks ekstraseluler, serta sel -sel sistem kekebalan tubuh. Agar sel -sel ini melakukan pekerjaan mereka, mereka tidak perlu pindah ke lokasi cedera. Gerakan ini, yang disebut migrasi, sangat bergantung pada aktin protein. Baik BPC-157 dan TB-500 penting dalam regulasi aktin BPC-157 bekerja pada tingkat gen untuk meningkatkan produksi aktin [1] .TB-500, protein pengikat aktin, membantu menyita aktin di daerah di mana ia paling berguna untuk membangun filamen dari aktin untuk memungkinkan gerakan sel [2]. Bersama-sama, BPC-157 dan TB-500 secara sinergis untuk meningkatkan kuantitas dan fungsi aktin dan dengan demikian meningkatkan laju fibroblast dan sel-sel sistem kekebalan tubuh yang bermigrasi ke area cedera.Picturan besar yang berkembang GrowthHormoneBaik TB-500 dan BPC-157 berinteraksi dengan hormon pertumbuhan dalam proses penyembuhan. BPC-157 Meningkatkan ekspresi reseptor hormon pertumbuhan pada fibroblas, meningkatkan evelevitas sel-sel ini dan dengan demikian kemampuan mereka untuk mempromosikan regenerasi jaringan lunak [3]. WithTB-500 di atas kapal, reseptor hormon pertumbuhan ekstra tidak akan sia-sia karena para fibroblas akan memiliki penyimpanan aktin yang memadai untuk memanfaatkan rentang hidup mereka yang memanjang. TB5-00, BPC-157, Kolagen, dan Sekretagog Hormon yang Pertumbuhan adalah SureFiray untuk meningkatkan tingkat luka, dan satu-satunya hormon.Tentang penulisLiteratur di atas diteliti, diedit dan diselenggarakan oleh Dr. E. Logan, M.D. Dr. Elogan memegang gelar doktor dari Case Western Reserve University School Ofmedicine dan gelar B.S. dalam biologi molekuler.Penulis jurna ilmiahAllan L. Goldstein, MD, Allan L. Goldstein is professor and Catharine B. & WiliamMcCormick Chair of the department of Biochemistry and Molecular Biology at TheGeorge Washington University School of Medicine and Health Sciences, where he hasserved since 1978. Thymosins were discovered in the mid 1960’s, when Allan Goldsteinfrom the Laboratory of Abraham White at the Albert Einstein College of Medicine in NewYork studied the role of the thymus in development of the vertebrate immune system. Heis a world-renowned authority on the thymus gland and the workings of the immunesystem, and co-discoverer of the thymosins. Dr. Goldstein is the author of over 400 scientific articles in professional journals, the inventor on more than 15 U.S. Patents, andthe editor of several books in the fields of biochemistry, biomedicine, immunology andneuro-science. He is on the editorial boards of numerous scientific and medical journalsand has been a consultant to many re-search organizations in industry and government;,co-founder of The institute for Advanced Studies in Aging and Geriatric Medicine, a non-profit research and educational institute; a member of the Board of Trustees of the AlbertSabin Vaccine Institute, and serves as the Chairman of the Board of Regene Rx Biopharmaceuticals. Dr. Goldstein received his B.S. from Wagner College in 1959 and hisM.S. and Ph.D. from Rutgers University in 1964. He served as a faculty member of theAlbert Einstein College of Medicine from 1964 to 1972, and moved to the University ofTexas Medical Branch in Galveston in 1972 as professor and director of the division of Biochemistry.
Allan L. Goldstein, MD is being referenced as one of the leading scientists involved in theresearch and development of TB-500 and other Thymosins. In no way is thisdoctor/scientist endorsing or advocating the purchase, sale, or use of this product for anyreason. There is no affiliation or relationship, implied or otherwise, between PeptideSciences and this doctor. The purpose of citing the doctor is to acknowledge, recognize.and credit the exhaustive research and development efforts conducted by the scientistsstudying this peptide. Dr. Goldstein is listed in [5]under the referenced citations.Sumber daya1.C.-H. Chang, W.-C. Tsai, M.-S. Lin, Y-H. Hsu, and J.-H. S. Pang, “The promotingeffect of pentadecapeptide BPC 157 on tendon healing involves tendon outgrowth,cell survival, and cell migration,”J.Appl. Physiol., vol. 110, no.3, pp.774-780, Oct[Physiology.org]
2.J. Kim and Y. Jung, “Potential Role of Thymosin Beta 4 in Liver Fibrosis,” Int. J.Mol. Sci., vol.16,no.5,pp.10624-10635,May 2015.[NCBI]
3.C.-H. Chang, W.-C. Tsai, Y.-H. Hsu, and J.-H.S.Pang,“Pentadecapeptide BPC157 enhances the growth hormone receptor expression in tendon fibroblasts,” Mol.Basel Switz.,vol.19,no.11,pp.19066-19077, NOV. 2014.[NCBI]
4.Song, Ran & Choi, Hyun & Yang, Hyung-In & Yoo, Myung & Park, Yong-Beom &Kim, Kyoung.(2012).Association between serum thymosin B4 levels of rheumatoidarthritis patients and disease activity and response to therapy. Clinicalrheumatology.31.1253-8.10.1007/s10067-012-2011-7.[Research Gate]
5.Philp, D., et al. “Thymosin β4 Promotes Angiogenesis, Wound Healing, and HairFollicle Development.”Mechanisms ofAgeing and Development, vol. 125, no. 2Feb.2004,pp.113-115,10.1016/i.mad.2003.11.005.[PubMed]
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